Neuroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Two distinct cell morphologies were appreciated and separated in a long-established culture line (CHP-100) of human neuroblastoma.
|
6825097 |
1983 |
Neuroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
While both SKNMC and CHP neuroblastoma cells expressed mRNAs for IGFBP-2, -4, and -6 no signal was detected for IGFBP-1, and -3 and only SK-N-MC cells expressed IGFBP-5 mRNA.
|
9404729 |
1997 |
Neuroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Chromosomal features of CHP-382/JK shared with other neuroblastoma cell lines were the deletion of 1p and the presence of extra 17q material.
|
2582423 |
1985 |
Neuroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our study investigated the processes undergone by CHP-212 neuroblastoma cells, after being treated with Casiopeínas® (Cas) IIgly, IIIEa, and IIIia for 2, 10, and 24 h.
|
31262895 |
2019 |
Neuroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The authors quantified the expression of 2,061 RNA transcripts related to oncogenesis and of 380 proteins expressed in SK-N-SH and CHP-134 NB cell lines in the presence or absence of 13-cis retinoic acid.
|
12972807 |
2003 |
Neuroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Most importantly, we show, that MK-5108 specific aurora A kinase inhibitor decreases neuroblastoma cell survival, and when used in combination with the mAb, significantly potentiates cytotoxicity against IMR-32, CHP-134, and LA-N-5 neuroblastoma cells in vitro.
|
23962557 |
2013 |
Neuroblastoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Two regions of deletion in 9p22- p24 in neuroblastoma are frequently observed in favorable tumors.
|
12072202 |
2002 |
Neuroblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Interferon regulatory factor-2 (IRF-2) repression of MHC class I and beta 2-microglobulin gene expression in CHP-126 neuroblastomas may demonstrate a mechanism by which virus persists in neural cells.
|
8550813 |
1995 |
Neuroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Although, there was no virtual stimulation of autophagy in the 14G2a mAb-treated CHP-134 neuroblastoma cells, we were able to show that PHLDA1 protein positively regulates autophagy and this process exists in a mutually exclusive manner with apoptosis in PHLDA1-silenced CHP-134 cells.
|
30027525 |
2018 |
Neuroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
We have recently shown that a novel, reversible MetAP2 inhibitor, A-357300, significantly inhibits CHP-134-derived neuroblastoma s.c. xenograft growth rate with a treatment-to-control (T/C) ratio at day 24 of 0.19 (P < 0.001) without toxicity.
|
15814649 |
2005 |
Neuroblastoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
As a first step towards the molecular analysis of the role these genes play in neural cells, we studied the expression of four human HOX genes in five neuroblastoma (NB) cell lines - SK-N-BE, CHP-134, IMR-32, SK-N-SH and LAN-1 - during the process of differentiation induced by treatment with retinoic acid (RA).
|
1981366 |
1990 |